A Comparative Study of Propofol and a Combination of Propofol with Fentanyl as Anaesthesia for Direct Laryngoscopic Biopsy of Laryngeal Growths
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 11
Abstract
Introduction: Direct laryngoscopy guided biopsy (DLB) is a short procedure which can b e s afely done under general anaesthesia with only Propofol or in combination with Opiods, without using any muscle relaxants. The aim of the present study was to compare Propofol and a combination of Propofol with Fentanyl as anaesthesia for Direct Laryngoscopic Biopsy of Laryngeal growths without using muscle relaxants. Materials and Methods: The present study was conducted on 60 patients aged between 30 to 70 years who presented with Laryngeal growths and were scheduled for elective Laryngeal Biopsy Results: A total of 60 patients between the age group 30 to 70 years were included in the study. They were ASA grade I, II and III, scheduled for Laryngeal biopsy under anaesthesia. Patients were randomized into two groups, 30 patients in each Group P and Group PF. Group P received only Propofol and Group PF received a combination of Propofol and Fentanyl. Patients were monitored during anaesthesia using continuous ECG, NIBP and Pulse Oximeters. Intra-operative IV fluids were given according to the protocols. Vital data was recorded preoperatively and during direct laryngoscopy at every 5 minutes interval. Preoperative vitals were same in both groups and statistically there was no significant difference in the data. Intraoperative pulse rates and mean arterial pressures during direct laryngoscopy and biopsy were raised in group P compared to group PF. Postoperative pulse rates and mean arterial pressures were raised in group P compared to group PF. Post-operative sedation was good in group PF patients compared to group P. Conclusion: To conclude, the study confirms that general anesthesia with a combination of Propofol and Fentanyl without apnoea is a simple, safe, suitable, devoid of hemodynamic stress is a better alternative compared to administration of only Propofol. Our findings also suggest that direct laryngoscopic guided biopsies can be done without administration of Succinylcholine.
Authors and Affiliations
G. Ramya, C. Geetha, B. Deepraj Singh
Keywords
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