A comparative study on parathyroid hormone among premenopausal and postmenopausal women
Journal Title: Medpulse International Journal of Physiology - Year 2017, Vol 4, Issue 3
Abstract
Background: Calcium is one of the main bone-forming minerals and an appropriate supply to bone is essential at all stages of life. Calcium plays important role in osteoporosis pathology. The two main regulators of calcium homeostasis are PTH and vitamin D. Objective: To compare parathyroid hormone levels in premenopausal and postmenopausal women. Material and Methods: The present study was a cross-sectional study conducted in Department of Physiology, Government Medical College, Latur. 30 premenopausal women with age between 38 to 45 years and 30 postmenopausal women between 50 to 57 years age group were selected from general population for the study. The study subjects with medical, surgical or gynecological abnormalities were excluded. The present study was approved by the Institution Ethical Committee. The informed written consent was taken from subjects. Results: Postmenopausal women had significantly lower serum calcium (8.13 ± 0.43) as compared to premenopausal women (9.36 ± 0.50) Postmenopausal women have significantly higher levels of serum parathyroid hormone as compared to premenopausal women but within the normal range limits and the difference was statistically significant (p<0.0001) Conclusion: This study suggests that there was increase in serum PTH levels in postmenopausal women as compared to premenopausal women.
Authors and Affiliations
Pratima D Khatake, Snehalata Mali
Keywords
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