Evaluation of the relationship between nitric oxide level and severity of Plasmodium falciparum malaria
Journal Title: Medpulse International Journal of Physiology - Year 2017, Vol 3, Issue 1
Abstract
Background: According to WHO’s estimated number of cases, India has the largest number of malaria cases occurring outside of Africa. Karnataka has the highest incidence of malaria in south India and in 2015 nearly 100 thousand cases were reported in this state, with 22 deaths. Malaria is a significant and serious health problem in Karnataka state and particularly in Dakshina Kannada (Mangalore) district. Methods: Blood samples were collected from both controls and patients for a series of laboratory investigations using standard protocols for estimation of hematological profile, nitrite / nitrate levels. Results: Significant decrease in hemoglobin level and thrombocytopenia were the two most important hematological abnormalities seen in our cases of acute malaria infection. The chances of anemia was related more to decrease in hemoglobin level, while, thrombocytopenia was associated with P. falciparum infection. Conclusion: All together, these results point out to the fact that nitric oxide is in fact a marker of clinical infections can be used as an indicator for the severity of the disease.
Authors and Affiliations
Shreyas Samaga, Shrikant L Patil
Keywords
Related Articles
- EP ID EP259184
- DOI -
- Views 273
- Downloads 0
Effect of increased adiposity on cardiorespiratory fitness of young Indian individuals
Incidence of obesity in early life is increasing nowadays because of faulty food habits and lack of exercise. This study was aimed to find out whether obesity affects cardiorespiratory efficiency of young adults. As VO2m...
Effect of nicotine on platelet function
Background: Tobacco is the dried and processed leaves of the plant Nicotiana tobacum that is widely cultivated and commercially grown in many countries of the world. In India, tobacco is taken in several other forms also...
Study of effect of cement dust on lung function in cement factory workers
Background: Normal function of lungs is an important aspect of healthy life which is neglected by many peoples. Chronic exposure to cement dust has long been associated with the prevalence of respiratory problems and air...
Effects of age on visual evoked potentials
Background: Pattern-reversal visual evoked potential (PRVEP) is an objective, sensitive and non-invasive neurophysiological test that can prove to be a useful clinical tool in investigating the physiology and pathophysio...
Study of pulmonary function tests in tobacco factory workers
Tobacco use is a risk factor for many diseases, especially those affecting the heart, liver, and lungs, as well as many cancers. In 2008, the World Health Organization named tobacco as the world's single greatest cause o...