A COMPARISON OF THE DIAGNOSTIC VALUE OF MAGNETIC RESONANCE MAMMOGRAPHY VERSUS ULTRASOUND MAMMOGRAPHY IN MODERATE- AND HIGH-RISK BREAST CANCER PATIENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 53
Abstract
BACKGROUND Due to the high prevalence of breast cancer, it is important to use screening methods for the diagnosis of early stages and faster treatment of this disease; better diagnosis should improve survival and quality of life for patients. Mammography, which is the preferred screening method for 40- to 70-year-old women, currently has limitations for the diagnosis of specific lesions. That is why screening with ultrasonography and magnetic resonance imaging (MRI) have recently received more attention. This study determined the sensitivity and specificity of these imaging methods in one hospital. MATERIALS AND METHODS This diagnostic descriptive study was conducted on women referred to surgical and gynaecological clinics of Rouhani Teaching Hospital in Babol, Northern Iran, who had a moderate or high risk of breast cancer. After MRI, the patients underwent ultrasonography and 6-month follow-up, with biopsies where needed. The researchers analysed the results to determine the diagnostic value of MRI and breast ultrasound, and to compare them. RESULTS A total of 106 women with an average age of 43.93 ± 11.51 years were included. Out of 57 people who had Breast ImagingReporting and Data System (BIRADS) 3 by the ultrasound, 44 (77%) people had BIRADS 3 on follow-up, but 13 people were in other groups. Of 59 people who had BIRADS 3 in the MRI, 54 (91%) had BIRADS 3 after the follow-up too. The sensitivity, specificity, positive and negative predictive values (PPV and NPV), and accuracy of ultrasound were 91.7%, 87.2%, 47.8%, 98.8% and 87.7%, respectively. These amounts were 100%, 98.9%, 92.3%, 100% and 99.1% for MRI, respectively. The difference for specificity, PPV and accuracy between ultrasound and MRI were significant (p=0.006, p=0.007, p=0.001, respectively), but not significant for sensitivity and NPV. CONCLUSION MRI has higher sensitivity, specificity and accuracy and less false positive and negative results for the early diagnosis of breast cancer in comparison with ultrasound.
Authors and Affiliations
Sara Yahyazadeh, Rahele Mehraeen
Keywords
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- EP ID EP550535
- DOI 10.14260/jemds/2018/1245
- Views 77
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