A Glance at the Cost of Chelation Therapy with Desferal and Exjade in Iran
Journal Title: Iranian Journal of Blood and Cancer - Year 2010, Vol 3, Issue 1
Abstract
Background: Thalassemia is a series of hemoglobinopathies in which the production of perfect hemoglobin is completely or partially suppressed. Using injectable iron chelators have been dominating treatment for the iron overload caused by recurrent blood transfusions in thalassemic patients, however, a new oral iron chelating drug (Exjade) have been recently introduced and might be cost effective compared to previous treatment methods. This study was undertaken to evaluate the cost of Exjade in comparison with injectable iron chelators. Patients and Methods: In this retrospective study, we calculated the cost of iron chelation with Deferoxamine mesylate or Desferal in three groups of patients including those with optimum moderate and poor compliance. Afterwards, we compared the cost with the cost of iron chelation using Exjade. The cost of drugs and treatment for complications caused by iron overload were both taken into account. Results: The average cost of treatment per year with Deferoxamine mesylate was 85601032 Rials for patients with poor compliance, 62739714 Rials for patients with moderate compliance, and 50118376 Rials for patients with optimum compliance. In addition, according to the latest price of Exjade in Iranian market, we found out a regular oral iron chelation therapy using Exjade, with a dose of 20 mg/kg, to cost 76650000 Rials per year. Conclusion: Our findings indicate that using Exjade is cost-effective for those patients who have poor compliance to parenteral treatment. More investigations should be implemented to find the social and economic impact of Exjade therapy on quality of life among patients needing iron chelation therapy.
Authors and Affiliations
M. Hadipour Dehshsal, MR. Shah Ahmad Ghasemi
Keywords
Related Articles
- EP ID EP373444
- DOI -
- Views 106
- Downloads 0
The Prevalence of Blood-Borne Viral Infection (HBV, HCV, HIV) among Hemophilia Patients in Hamedan Province of Iran
Background: Hemophilia A and B are the most frequent congenital coagulation disorders. This study was conducted to determine the prevalence of hepatitis B, C and human immunodeficiency viruses among hemophilic patients i...
Myelofibrosis due to Secondary Hyperparathyroidism in a Case of Celiac Disease
Myelofibrosis is reported in patents with primary hyperparathyroidism. It is also was reported in patents with sec- ondary hyperparathyroidism due to end-stage renal disease or Vitamin D dependent rickets .We present a c...
University Students Awareness and Attitude towards Blood Donation in Kerman City
Background: Blood transfusion is one of the most crucial needs of the society in multiple diseases and injuries. The only source of blood is donation. Students consist a large and healthy group who are able of providing...
Intra articular Injection of Rifampin in Iranian Children with Haemophilic Arthropathy
Background: Chronic synovi tis is one of the most important complications in haemophilic patients. Rifampin is an antibiotic which its intra-articular injection leads to destruction of the synovial membrane of hemophilic...
Relation between the Short Term Health Related Quality of Life and Various Types of Medical Treatment in Patients with Idiopathic Chronic Thrombocytopenia
Background:Chronic Idiopathic Thrombocytopenic Purpura (ITP) is an autoimmune disorder characterized by a low platelet count due to reduced production and higher destruction of the platelets. Therapy is aimed at increasi...