A prospective randomized double blind study to compare the effects of dexmedetomidine and fentanyl on intubating conditions during awake fiberoptic bronchoscopy guided intubation
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 3
Abstract
Introduction Various drugs have been used for sedation to provide adequate intubating conditions during awake fiberoptic intubation AFOI but these drugs may cause excessive sedation followed by respiratory depression which is undesirable in these patientsSo this study was planned with aim to compare dexmedetomidine with fentanyl for conscious sedation during AFOI in adult patients posted for various elective surgical procedures under general anaesthesiaMaterials and Methods Sixty adult patients were randomly allocated into two groups with 30 patients each After pre operative evaluation and informed consent patients were given pre anaesthetic medication followed by airway nerve blocks Group A n30 Dexmedetomidine Group received intravenous IV dexmedetomidine 15 gkg diluted in 100 ml normal saline NS over 10 min and Group B n30 Fentanyl Group received IV fentanyl 2 gkg diluted in 100 ml NS over 10 min After achieving adequate sedation RSS 2 awake fiberoptic bronchoscopy and intubation was done Intubating conditions oxygen desaturation caused tolerance to intubation and haemodynamic changes along with adverse effects were observed and noted in both groupsResults Cough score and intubation comfort scores were significantly better in Group A when compared to Group B P 005Conclusion Dexmedetomidine 15 gkg is preferable over fentanyl 2 gkg for conscious sedation during AFOI as it provides more favourable intubating conditions with minimal haemodynamic changes and adverse effectsKeywords Awake fiberoptic intubation Conscious sedation Dexmedetomidine Intubating conditions Fentanyl Oxygen desaturation
Authors and Affiliations
Neena Jain, Veena Patodi, Bhawesh Upreti, Surendra K. Sethi, Satveer S. Gurjar
Keywords
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- EP ID EP476511
- DOI 10.18231/2394-4994.2018.0078
- Views 95
- Downloads 0
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