A Prospective Study on Incidence of Bone Metastases at Various Prostate Specific Antigen Levels in Carcinoma Prostate in South Indian Population
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 1
Abstract
Introduction: Globally prostate cancer is the second most frequently diagnosed cancer in men and the fifth most common cancer overall. Several Indian registries have revealed an increasing trend in the incidence of prostate cancer. Prostate cancer has a tendency to metastasize to bone. On presentation, up to 14% of patients have bone metastasis. Radionuclide bone scanning being the most sensitive method plays an important role in detecting bone metastasis in prostate cancer. The aim of this study is to study the incidence of bone metastases of the south Indian population at various PSA levels in carcinoma prostate and to determine whether the probability of positive bone scan result of newly diagnosed Carcinoma Prostate patients can be predicted by serum PSA level, with an attempt to define a particular PSA level under which the group of patients would have low risk of obtaining a positive bone scan, so that the radiologic procedure can be safely omitted. Material ans methods: This prospective study was conducted in Department of Urology, at Sri Venkateswara Institute of Medical Sciences, Tirupati from May 2016 to august 2017. All patients who were diagnosed to have carcinoma prostate on TRUS guided biopsy or in TURP chips were subjected to bone scans. Results: Because of high incidence of bone metastases in south Indian population, it is better to undergo bone scan in newly diagnosed carcinoma prostate even with sr. PSA <20ng/ ml. Conclusion: Because of high incidence of bone metastases in south Indian population, it is better to undergo bone scan in a newly diagnosed carcinoma prostate even with sr. PSA <20ng/ml.
Authors and Affiliations
Bhargava Reddy K. V, Muni Prasad M
Keywords
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