A Review: Effect of Permeation Enhancers on the Penetration Mechanism of Transdermal Gel
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 1
Abstract
Transdermal systems are non-invasive, convenient, and inexpensive and can be self-administered. They can provide sustained plasma concentration profile for long periods of time. The systems can greatly improve patient compliance through avoidance of first-past metabolism, improved bioavailability, reduction of systemic side effects and dosing schedule. In the past three decades, transdermal drug delivery has been developed to the stage where transdermal systems become a feasible way of delivering clinically effective drugs particularly those drugs with significant first-pass effect of the liver that can prematurely metabolize drugs. The advantages of this type of drug delivery include targeting specific areas of the body and decreasing the amount of drug necessary for effect as compared to drugs taken orally.
Authors and Affiliations
Sarabjeet Singh, Kamal Saroha, Himanshi3 .
Keywords
Related Articles
- EP ID EP383314
- DOI 10.9790/3008-11128289 .
- Views 58
- Downloads 0
Correlation of Serum and Urinary Magnesium with eGFR in Chronic Kidney Disease Patients
Aim And Objectives: The aim of our study is to correlate eGFR with serum and urinary magnesium levels in CKD patients. Material And Methods: This study is a prospective studywith total of 30 CKD patients(stages II-V) adm...
Antimicrobial Activity of Seed Extracts from Albizia bernieri E. Fourn. (Fabaceae)
This work aimed at assessing the antimicrobial activity of Albizia bernieri seed extracts. Methanol extract (SME), alkaloids extracted under basic (Alk1) and acidic (Alk2) conditions, polar saponosides (Sap1) and less po...
Renal Length and Its Relationship with the Height of an Individual: A Review
Kidney plays an important role in our body such as excretes metabolic wastes, maintaining the equilibrium between fluid and electrolyte, control of blood pressure, erythropoiesis etc. Loss of kidney mass and kidney funct...
Effects of Ampiclox andAmoxicillin on thePharmacokinetics of Metformin in Type II Diabetic Patients
Infection is common in diabetes and in the course of treatment,ampiclox and amoxicillin may be coadministered with metformin. The study was designed to evaluate the effects of co-administration of ampiclox and amoxicilli...
Evaluation of In-vivo Curative and Haematopoietic Effect of Three Chinese Teas in Plasmodium bergheiInfectedMice
The emerging resistance of Plasmodium species to currently available antimalarial drugs remains a public health problem, hence the need for new effective, safe and affordable drugs. The curative and haematopoietic activi...