A Review on Current Trends of Nanotechnology for Cancer Therapy
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2018, Vol 8, Issue 6
Abstract
Targeted drug delivery is an advanced method of delivering drugs to the patients in such a targeted sequences that increases the concentration of delivered drug to the targeted body part of interest only (organs/tissues/ cells) which in turn improves efficacy of treatment by reducing side effects of drug administration. Basically, targeted drug delivery is to assist the drug molecule to reach preferably to the desired site. Thus, targeted delivery systems are urgently needed to achieve desire drug delivery efficiency, improve therapeutic efficacy in the targeted cells/tissues, and minimize toxic effects. Colloidal drug delivery vehicles have been studied in the laboratory for more than 30 years, but the few liposome based formulations already on the market are mainly concerned with reducing the side effects of the encapsulated drugs liposomes nanoparticles which show diminished phagocytosis have been developed and the range of sites which can be reached has been extended. In the past two decades there have been major advances in the development of niosomal drug delivery systems suitable for applications ranging from cancer chemotherapy to gene therapy. In general, an optimized system consists of niosomes with a range of 10-100 nm these formulation is more stable than liposomes.
Authors and Affiliations
Bondar Ganesh H. , Nagoba S. N. 1, Pattewar Shraddha G, Vijendra Swamy, Thonte S. S. 1
Keywords
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