A Seven Years Retrospective Study of Prevalence of Viral Infections in Diverse Cancer Patients Admitted for Treatment in a Regional Cancer Center
Journal Title: GUJARAT CANCER SOCIETY RESEARCH JOURNAL - Year 2018, Vol 20, Issue 2
Abstract
Human Immunodeficiency Virus (HIV), Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) are public and global health problems. The study of serolprevalance is important to assess magnitude of disease transmission and aid in devising preventing measures. This was a retrospective analysis carried out in department of Microbiology, GCRI from January 2011 to December 2017. Between this periods a total of 2,07,258 blood samples were received for screening of HbsAg, 1,97,172 samples for HIV antigen and antibody and 1,68,282 for anti-HCV from different units of the hospital. All samples were tested by Enzyme Linked Immuno Sorbent Assay (ELISA) on fully automated ELISA system. Infection rate of HBV was 3.09%, HIV was 0.80%, and HCV was 0.59% in cancer patients in GCRI. Prevalence rate was higher in females as compared to males i.e. 0.49% vs. 0.31% for HIV infections, whereas it was more in males as compared to females for HCV and HBV i.e. 0.35% vs. 0.24% and 2.06% vs. 1.04% respectively. Serolprevalance of blood borne viral infection was found to be highly significant (p=0.0001) as compared to the healthy donors in GCRI. Over a period of seven years prevalence rate of HBV and HCV shows declining trends in the hospital from 4.41% to 2.55% and 0.68% to 0.42% respectively. In order to prevent transmission of these infections, educational program and screening to target group as well as illiterate people in collaboration with health care providers are required.
Authors and Affiliations
Foram Patel, Parijath Goswami, Hiren Patel
Keywords
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