Journal Club/Guest Lecture/ Review Lecture Presentations
Journal Title: GUJARAT CANCER SOCIETY RESEARCH JOURNAL - Year 2018, Vol 20, Issue 1
Abstract
Journal Club/Guest Lecture/ Review Lecture Presentations
Journal Club/Guest Lecture/ Review Lecture Presentations
Isochromosome der(17)(q10)t(15;17) with an Additional Copy of RARa-PML Fusion Gene in Two Young APML Patients
Acute promyelocytic leukemia (APML) is associated with the t(15;17)(q22;q21) translocation. The two chimeric genes, PML-RARa and RARa-PML are reported to play a role in leukemogenesis. Isochromosome of the long arm of th...
Significance of Variable Number Tandem Repeats (VNTR) Polymorphism of Thymidylate Synthase Gene in Patients with Colorectal Cancer: A Preliminary Study
5-fluorouracil (5-FU) is the most frequently used chemotherapeutic agent in the treatment of colorectal cancer (CRC) both in adjuvant and in palliative therapy. This drug mainly acts by inhibiting the activity of its tar...
Isolated Central Nervous System Blast Crises in Chronic Myelogenous Leukemia
Chronic myeloid leukemia (CML) is a chronic myeloproliferative disorder, currently treated with tyrosine kinase inhibitors. Uncontrolled CML eventually progresses to accelerated and blast crises, which is often medullary...
Effectiveness of Low Dose Rasburicase in Prevention and Treatment of Adult Tumour Lysis Syndrome: A Case Series Study
Rasburicase, a recombinant urate oxidase product, is safe and effective in lowering serum uric acid. A schedule of rasburicase at a dose of 0.15-0.2 mg/kg given once daily intravenously for 5-7 days has been recommended...
Randomized Study of Oral Misoprostol for Cervical Ripening before Intracavitary Brachytherapy for Carcinoma Uterine Cervix
Intracavitary brachytherapy forms an integral part of treatment of carcinoma cervix and the complications arising out of the procedure are partly related to the difficulties in cervical dilatation. This study aims to eva...