A Study of Bacterial Profile and Antibiotic Susceptibility Pattern of Chronic Suppurative Otitis Media among Patients attending a Tertiary Care Centre, Davangere
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2014, Vol 2, Issue 5
Abstract
Chronic Suppurative Otitis Media (CSOM) is a potentially serious disease because of its complications. The incidence of CSOM is increasing in the developing countries because of the poor hygiene practices and lack of health education. Knowledge of bacterial etiolgy of CSOM and their antibiotic susceptibility pattern prevalent in a community is very important for the clinicians for appropriate management of the cases and to prevent or minimise the occurrence of complications. The aim of this study was to determine the bacterial pathogens associated with CSOM and to study their antimicrobial susceptibility pattern from Davangere and its surrounding region. The study was carried out in a tertiary care centre in Davangere from June 2013 to November 2013 for a period of six months. The ear discharges from 118 patients with a clinical diagnosis of CSOM were collected and were subjected to aerobic culture & sensitivity. Out of 118 ear discharge samples cultured, 90(76.27%) samples yielded pure cultures, 16(13.56%) yielded mixed cultures while 12 samples (10.17 %) yielded no growth. From 90 pure isolates, the most common was Pseudomonas species (spp)(42.22%) followed by Staphylococcus aureus(34.44%). Drug sensitivities pattern among pure isolates showed that Cefoperazone was active against majority 89.47%. Pseudomonas isolates followed by Piperacillin 86.84% and Amikacin and Gentamicin in 84.21% cases, while Ofloxacin and Ciprofloxacin were effective against 50.0% and 47.37% isolates respectively. Staphylococcus aureus were sensitive to Amikacin in 90.32% of cases, Gentamicin, Cefoperazone and Piperacillin 83.87%, Ofloxacin 80.65%, and Erythromicin and Ciprofloxacin in 67.74% isolates, whereas only 12.90% and 16.13% isolates showed sensitivity to Ampicillin and Amoxyclav respectively. Pseudomonas spp is the most commonly isolated bacteria followed by Staphylococcus aureus in CSOM from our region. Majority of the isolates of Pseudomonas spp and Staphylococcus aureus isolates are sensitive to Amikacin, Gentamicin, Piperacillin, and Cefoperazone .Pseudomonas spp is becoming gradually resistant to Fluoroquinolones, while majority of the Staphylococcus aureus isolates are resistant to Penicillin drugs. Keywords: Pure culture, Mixed culture, Antibiotic susceptibility, Chronic Suppurative Otitis media (CSOM), Davangere
Authors and Affiliations
KG Raghu Kumar, S Navya, KG Basavarajappa
Keywords
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