A study of blood gas analysis and electrolytes in 50 cases of chronic cor pulmonale
Journal Title: MedPulse -International Medical Journal - Year 2015, Vol 2, Issue 12
Abstract
Abstract: The term ‘cor pulmonale’ if broken into its constituents cor (heart) and pulmonale (lungs) means cardiac involvement due to pulmonary disease. The term cor pulmonale was introduced in 1957 by Stuart Harris to denote right heart failure associated with a wide variety of diseases of the lung parenchyma, airways, thoracic cage and respiratory control mechanisms. The basic lesion in cor pulmonale is pulmonary hypertension. The clinical manifestations of cor pulmonale relate to alterations in cardiac output, salt and water homeostasis and in most cases, gas exchange in the lungs. Aim and objectives: of this study is to study the clinical features, and chest X-ray, electrocardiographic, echocardiographic features of chronic cor pulmonale. types of acid-base disturbances and serum electrolyte changes – their relation to blood gas abnormalities in chronic cor pulmonale. Fifty patients of chronic cor pulmonale were studied. Majority of patients were in the age group of 50-70 years. Cor pulmonale was seen predominantly in male patients and majority of patients were smokers, chronic bronchitis with emphysema was the major etiological factor. Majority of patients had obstructive defect on spirometry. Majority of patients were had hypoxia, hypercapnia and compensated chronic respiratory acidosis. Super imposed metabolic alkalosis were seen in significant number of patients. Serum sodium and potassium were normal in majority of patients with increasing PaCO2, the serum bicarbonate concentration progressively increased and the serum chloride concentration progressively decreased.
Authors and Affiliations
A Manjula, Chandrashekar Chandrashekar
Keywords
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