A study of correlation of HbA1c and homocysteine level in type II diabetic patients at tertiary health care centre

Journal Title: Medpulse International Journal of Biochemistry - Year 2018, Vol 8, Issue 2

Abstract

Background: Diabetes mellitus (DM) is a group disorder characterized by hyperglycemia resulting from defects in insulin secretion or insulin action. Aims and Objectives: To Study correlation of HbA1C and homocysteine level in type II diabetic patients at tertiary health care centre. Methodology: This was a cross-sectional study carried out in the Department of Medicine of a tertiary health care centre during the one year period i.e. January, 2017 to June, 2018 in the oneyear period there were 42 patients were enrolled to study, all the patients with the written consent were undergone with the routine testing were undergone HbA1 C level and homocysteine level in the biochemical laboratory. The statistical analysis was done by unpaired t-test and analyzed by SPSS 19 version of the software. Result: In our study we have seen that The majority of the patients were in the age group of 40-50 were 31.25%, followed by 27.08%, 30-40 were 18.75% , >60 were 16.67%,20-30 were 6.25%. The majority of the patients were Male i.e. 56.25%, and Female were 43.75% The level of Homocysteine was significantly higher as the Glycemic control become poor as t = 9.6487 df = 30 p<0.0001 (A vs C), t = 30.1886 df = 29, p<0.0001) (A vs D). Conclusion: It can be concluded from our study that level of Homocysteine was significantly higher as the Glycemic control become poor hence Homocysteine may be marker of complicated Diabetes and associated marker of cardiac diseases.

Authors and Affiliations

Vijay Mohan M, Mohammad Rafi

Keywords

Related Articles

Relationship between glycemic control and serum uric acid level in acute myocardial infarction

Background: Recent data have suggested that serum uric acid (SUA) level is positively associated with the development of type 2 diabetes (T2DM). We also know that diabetes is also independent risk factor for cardiovascul...

Study of role of serum LDH in carcinoma of breast as a prognostic biomarker

Background: Carcinoma breast is commonest cancer in urban and rural females in India. Presently, India already has one of the worst survivals from breast cancer, in the world. Cancer is a group of diseases that cause cel...

Study of uric acid in metabolic syndrome and it's correlation with individual components of metabolic syndrome

Aim: This study was designed to determine levels of serum uric acid (SUA) in patients of metabolic syndrome (MetS) and its correlation with individual components of MetS. Material and Methods: This was cross sectional st...

Novel concept of non-HDL cholesterol - A predictor of cardiovascular disease risk in type II diabetes mellitus patients

Background and Aim: Non-communicable diseases (NCDs) such as coronary artery disease (CAD) and diabetes mellitus (DM) are assuming importance due to an accelerating rate of morbidity and mortality. The overall mortality...

Study of plasma fibrinogen in diabetes mellitus with complications

Diabetes mellitus is a complex syndrome catheterized by hyperglycemia, leading to vascular complications such as retinopathy, nephropathy and macrovascular diseases like atherosclerosis. Diabetes patients with and witho...

Download PDF file
  • EP ID EP442159
  • DOI 10.26611/1002827
  • Views 207
  • Downloads 0

How To Cite

Vijay Mohan M, Mohammad Rafi (2018). A study of correlation of HbA1c and homocysteine level in type II diabetic patients at tertiary health care centre. Medpulse International Journal of Biochemistry, 8(2), 48-50. https://europub.co.uk/articles/-A-442159