A study of correlation of HbA1c and homocysteine level in type II diabetic patients at tertiary health care centre
Journal Title: Medpulse International Journal of Biochemistry - Year 2018, Vol 8, Issue 2
Abstract
Background: Diabetes mellitus (DM) is a group disorder characterized by hyperglycemia resulting from defects in insulin secretion or insulin action. Aims and Objectives: To Study correlation of HbA1C and homocysteine level in type II diabetic patients at tertiary health care centre. Methodology: This was a cross-sectional study carried out in the Department of Medicine of a tertiary health care centre during the one year period i.e. January, 2017 to June, 2018 in the oneyear period there were 42 patients were enrolled to study, all the patients with the written consent were undergone with the routine testing were undergone HbA1 C level and homocysteine level in the biochemical laboratory. The statistical analysis was done by unpaired t-test and analyzed by SPSS 19 version of the software. Result: In our study we have seen that The majority of the patients were in the age group of 40-50 were 31.25%, followed by 27.08%, 30-40 were 18.75% , >60 were 16.67%,20-30 were 6.25%. The majority of the patients were Male i.e. 56.25%, and Female were 43.75% The level of Homocysteine was significantly higher as the Glycemic control become poor as t = 9.6487 df = 30 p<0.0001 (A vs C), t = 30.1886 df = 29, p<0.0001) (A vs D). Conclusion: It can be concluded from our study that level of Homocysteine was significantly higher as the Glycemic control become poor hence Homocysteine may be marker of complicated Diabetes and associated marker of cardiac diseases.
Authors and Affiliations
Vijay Mohan M, Mohammad Rafi
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