A Study of Duodenal Ulcer Perforation Post-operative Outcome in A Tertiary Center
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 7
Abstract
Introduction: Time trends in the epidemiology of perforated peptic ulcer disease reflect complex, multifactorial etiologies. Based on today’s fast and instant lifestyle, it is evident that the epidemiology of peptic ulcer disease largely reflects environmental factors, primarily Helicobacter pylori infection, nonsteroidal anti-inflammatory drug (NSAID) use, and smoking. Aim: The aim is to study the relationship between post-operative morbidity and comorbid illness and pre-operative risk factors in cases of duodenal ulcer perforation. Methods: All non-malignant and non-traumatic duodenal ulcer perforation cases above the age of 12 years were taken. A total of 50 cases of duodenal perforation were studied over 18 months. The patients were treated with perforation closure with live omental patch repair after initial resuscitation and correction of electrolyte imbalances under the cover of broad-spectrum antibiotics. Results: 24 patients had smoking history and 19 patients had history of alcohol consumption. 29 patients had the previous history of peptic ulcer disease. 17 patients had the history of NSAID intake. The size of the perforation >0.5 mm was noted in 23 patients. The amount of peritoneal contamination >1 L was noted in 29 patients. 8 patients had wound infection, 3 patients had septicemia, electrolyte abnormalities were encountered in 21% of patients, and morbidity rate was 17.02%. Conclusion: Age, associated comorbid conditions, duration of symptoms, and clinical condition at the time of presentation all contribute in determining the post-operative morbidity and mortality.
Authors and Affiliations
S Senthil Arumugam, G Parthiban, A Ramprasad, Heber Anandan
Keywords
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