A study of prevalence of pulmonary Tuberculosis in HIV positive individuals and its association with CD4 count in RIMS Medical college & Hospital, Ongole, Andhra Pradesh
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Background: In recent years , the incidence of Human immunodeficiency virus (HIV) infection has increased enormously all over the world. patients with HIV infection are known to have risk of developing TB. case fatality rate is high with drug resistant TB in Aquired immunodeficiency syndrome(AIDS). Material and methods: This is an observational study of prevalence of pulmonary tuberculosis in HIV positive individuals conducted in the Department of Pulmonary medicine from September 2016 to August 2017 in RIMS Medical College and Hospital , Ongole ,Andhra Pradesh, India. Results: Out of 1016 patients, a total of 227 (22.35%) were diagnosed as Pulmonary tuberculosis. It was commoner in males (64%), and more frequent in laborers (46%)and Out of Total 227 HIV TB co-infection individuals 115 (50.67%) had CD4 counts of less than 200, in 49 (21.58%) patients between 200 & 349, in 38 (16.74%) patients between 350 & 500 and in 25(11.01%) patients. The results of the study emphasize that coinfection of TB in HIV/AIDS patients is a concern. There is direct correlation between CD4 counts depletion and Pulmonary TB in HIV/AIDS patient. Hence, regular monitoring of these patients is warranted. Conclusion: Reduction of CD4s in HIV infected patients below 500 associates with increasing prevalence of pulmonary tuberculosis . Early diagnosis of TB and prompt institution of Anti retro viral therapy reduces the prevalence of pulmonary tuberculosis mortality and morbidity significantly.
Authors and Affiliations
Dr. M. Venkatarao, Dr. N. Harsha vardhan2
Keywords
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- EP ID EP361397
- DOI 10.9790/0853-1702031216
- Views 58
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