A Study on Echocardiographic Findings And Qt Interval In Cirrhotic Patients And its Correlation With The Severity of Cirrhosis
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 9
Abstract
Context: Liver cirrhosis is refers to a condition of progressive disease that damages the normal architecture of the liver and it is caused by a number of conditions. This study observed that increasing frequency of QTc prolongation with worsening Child Pugh score and it correlated with a decreased heart rate Variability and these two become independent prognostic factors. Aim Of The Study: To assess whether QT interval prolongation and left ventricular end diastolic dimension abnormality will occur in cirrhosis, To assess whether the severity of cirrhosis is correlating with the QT interval prolongation and left ventricular end diastolic dimension. To use these two paraclinical parameters in all advanced stage cirrhosis patients as a screening tool to assess cardiovascular complications. Settings And Design: Prospective observational study . Materials And Methods : This study was conducted among 100 patients diagnosed with cirrhosis of liver got admitted in general medicine wards and medical gastroenterology ward at Government Rajaji Hospital, Madurai. From January 2015 to August 2015. Statisticalanalysis : One way ANOVA, Pearson correlation and Chi square test. Results : There was a linear relation between QTc prolongation and left ventricular end diastolic dimension and severity of cirrhosis. Conclusions : The frequency of QTc interval prolongation was statistically significant with worsening of child Pugh score. It indicates an association between QTc prolongation and the severity of cirrhosis.
Authors and Affiliations
Subramani Sujatha, Kandan Muralidharan
Keywords
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