A Study on Hepatic aminotransferases among elderly hypertensive patients: a population based observation
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2014, Vol 2, Issue 1
Abstract
Objective: To study the relationship of Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) with elderly hypertensive patients. Materials and methods: 95 elderly patients aged between 50 to 75 years of either sex and 92 age and sex matched control individuals were recruited into the study, after obtaining their informed consent. Serum AST and ALT levels of both the groups were analysed statistically. Results: Serum ALT level was significantly higher in HTN group than in control group (p < 0.05). However, no significant difference in AST levels was observed in two groups. Conclusion: ALT, beside its potential as a marker of hepatic disorders, may also be useful for timely detection of HTN and its subsequent deleterious consequences among elderly population.
Authors and Affiliations
Roy Himansu| MS, Associate Professor, Department of General Surgery, Medical College Kolkata, India., Dan Subhasish| MD, Demonstrator, Department of Biochemistry, Medical College Kolkata, India., Rahaman Musfikur| MD, Assistant Professor, Department of Pharmacology, Medical College Kolkata, India., Banerjee Prithwijit*| MD, Demonstrator, Department of Pharmacology, Medical College Kolkata, India., Adak Shiuli Roy| MD. Associate Professor, Department of Biochemistry, North Bengal Medical College, Darjeeling, India.
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