“A Study on Lipoprotein (A) Levels in Ischemic Stroke among Diabetics and Non-Diabetics”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 6
Abstract
Introduction: Cerebrovascular accident is defined as the abrupt onset of focal neurological deficit. Type 2 diabetes mellitus is a major risk factor. Dyslipidaemia also plays a major role as a risk factor for stroke. Background: Studies in the past have demonstrated that patients with increased lipoprotein (a) and diabetes have an increased risk of stroke. High lipoprotein (a) predicts risk of early atherosclerosis independently of other risk factors including LDL. Objective: To compare lipoprotein (a) levels in type 2 diabetics and nondiabetic patients with ischaemic stroke. Methods: Cross sectional, prospective study done at the Institute of Internal Medicine, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai from August 2016 to June 2017. 100 patients with ischaemic stroke were included, with 50 patients who were type 2 diabetics, and 50 patients who were non-diabetics. Results: Total of 100 patients were included in our study. 50 patients had type 2 diabetes and 50 patients were non-diabetic. 62 patients were male and 38 patients were female. The mean age was 57 years, with a range from 42 to 73 years. Lipoprotein (a) values of 15-30 was present in 17 diabetic patients and 27 non-diabetic patients, and a value of 30-50 was present in 33 diabetic patients and 23 non-diabetic patients. This association between lipoprotein (a) value and ischaemic stroke is significant (p value 0.044).
Authors and Affiliations
Dr. R. Penchalaiah, Dr. G. Subbaraghavalu
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