Study on the Prevalence of Thyroid Disorders and Thyroid Autoimmunity among Type 1 Diabetics.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 3
Abstract
Introduction: Type 1 Diabetes is a common autoimmune endocrine disease in children and adolescents. The presence of auto antibodies targeted against β-cell antigens represents the autoimmune character of Type 1 Diabetes. Due to this autoimmune basis, individuals with Type 1 Diabetes are at increased risk for the development of additional autoimmune disorders compared with the general population. Material & MethodsA cross sectional observational study to analyse the prevalence of thyroid disorders and thyroid autoimmunity among Type 1 Diabetes in Department of General medicine, Government General Hospital, Guntur Medical College, Guntur.Established cases of Type 1 Diabetes , diagnosed based on standard criteria were included. Results: Out of the 64 study population, total number of hypothyroid patients were 8 (12.5%). Majority (7 out of 8 cases) were having subclinical hypothyroidism. With regards to thyroid autoimmunity status, total number of patients positive for Thyroid Peroxidase Antibodies (TPOA) were 12 (18.75%). Total number of TPOA patients with hypothyroidism were 58% (7 out of 12) and total number of hypothyroid patients with TPOA were 87.5% (7 out of 8).Conclusions: Study confirms the association between autoimmune hypothyroidism and type 1 diabetes and suggests that all subjects with type 1 diabetes, particularly those with positive Thyroid Peroxidase antibodies, should undergo annual screening by serum Thyroid Simulating Hormone measurement to detect asymptomatic thyroid dysfunction.
Authors and Affiliations
Dr. ReddiJagannadham, Dr. Sigamani Sunitha
Keywords
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