A Study on Synthesis, Characterization and DNA-binding<br /> of Ruthenium(II) complex: [Ru(bpy)2(ipbh)](ClO4)2<br />
Journal Title: Science Paper Online - Year 2006, Vol 1, Issue 1
Abstract
In this study, the DNA-binding of ruthenium(II) mixed-ligand complex containing 2,2'-bipyridine [Ru(bpy)2(ipbh)(ClO4)2 (bpy = 2,2'-bipyridine, ipbh =3-(1H-Imidazo[4,5-f][1,10]phenanthrolin2-yl)-1-benzodioxane) has been synthesized and characterized by elemental analysis, ES-MS and 1H-NMR spectra. The interaction of the complex with calf thymus DNA (CT-DNA) was investigated by absorption titration, thermal denaturation, viscosity measurements. The results suggest that the complex binds with CT-DNA by intercalation mode.
Authors and Affiliations
Yunjun Liu, Wenjie Mei, Ruijie Wang
Keywords
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