A study on the seroprevalence of cytomegalovirus infection in patients with coronary artery disease in a tertiary care hospital
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 4
Abstract
Introduction Coronary artery disease CAD is a leading cause of death in developing and developed countries Infectious etiology is also suspected to be a significant risk factor in these cases CMV is a beta herpes virus Once infected the person carries the virus for life80 adults show CMV specific antibodies in their serum indicating the high prevalence of CMV infectionAim To know the seroprevalence of CMV infection in patients with CADMaterials and Methods Clinically stable patients undergoing coronary angiography because of symptoms suspected of CAD were included in the study The samples were tested for specific antiCMV IgG antibodies by ELISAResults Of 150 patients 86 had detectable quantities of antiCMV IgG antibodies in their serum 15 patients 10 were found to be borderline positive and the antibody index was between 09 to 11 6 patients 4 did not have detectable quantities of antiCMV IgG antibodies in their serum Prevalence of CAD was 100 in the study groupConclusion Cytomegalovirus is an essential cause of atherosclerosis due to the infectious burden In the study population 86 of the patients showed elevated levels of antiCMV IgG antibody So there is an association between CMV infection and coronary artery diseaseKeywords Coronary artery diseases Cytomegalovirus Infection
Authors and Affiliations
Prabhu Vairavel, C. P. Ramani
Keywords
Related Articles
- EP ID EP485892
- DOI 10.18231/2581-4761.2018.0058
- Views 88
- Downloads 0
Study of Vulvo-Vaginal Candidiasis among Patients Visiting Obstetrics and Gynecology Department in a Tertiary Care Centre
Background: Vulvovaginitis is a common day to day problem in gynecological practice. Candida albicans is the commonest infectious cause. An estimated 75% of women have at least one episode of Vulvo-vaginal Candidiasis an...
Characteristics, virulence factors and antibiogram of Acinetobacter spp. and Moraxella catarrhalis isolates from a tertiary care hospital in India
Non-fermenting Gram negative bacteria are very common causes of infection in the hospital. They are often resistant to multiple antibiotics and very difficult to treat. We here present a compilation of data regarding iso...
Isolation & study of multidrug resistant Acinetobacter from various clinical samples in a tertiary care hospital
Introduction: Nosocomial infections with Acinetobacter are being increasingly reported worldwide from debilitated& Critical care patients. Multidrug resistance among Acinetobacter are now a major cause of concern. So the...
Antibiotic resistance pattern of Uropathogens in a tertiary care hospital of Central India
Background: Urinary tract infection is one of the most common bacterial infections in human being. The causative agent of UTI varies from place to place and they also vary in their resistance pattern. Objective: This stu...
Organizing a Reference Laboratory for Medical Mycology
The objective is to provide the conceptual basis as well as some specifics needed for establishing a laboratory for mycology. A functional self-contained mycology laboratory, include three definitive areas, a clerical of...