Study of Antifungal susceptibility for Fluconazole and Clotrimazole of Candida Species by disc diffusion method in a Tertiary care centre in Karnataka
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2016, Vol 2, Issue 3
Abstract
Background: Vulvo-vaginitis is a common day to day problem in gynecological practice. Candida albicans is the commonest infectious cause. There is limited data regarding the antifungal susceptibility of yeast causing Vulvo-vaginal candidiasis, since isolation by cultures are rarely performed, hence the present study was undertaken. The main objective of this study is to find out the Antifungal susceptibility for Fluconazole and Clotrimazole of Candida Species by disc diffusion method among patients visiting Obstetrics and Gynecology Department of AJ Institute of Medical Sciences, Mangalore. Methods: Vaginal swabs were collected from 100 patients visiting the hospital with history of white discharge and subjecting it to microscopy and culture. Candida isolates were further identified to species using conventional methods. Disc diffusion testing of each isolate with Fluconazole and Clotrimazole was performed as described in CLSI (formerly NCCLS) document M44-A. Results: In our study antifungal susceptibility test was by disc diffusion method. The sensitivity of the isolates in our study to Clotrimazole was 81% and to Fluconazole was 83.7%. Conclusion: To conclude, as the antifungal resistance does not seem to be a major problem in the general population, it may be appropriate to use courses of antifungal treatment in women with vulvovaginal candidiasis.
Authors and Affiliations
Bhavana J, Yudukul. S, Anitha KB
Keywords
Related Articles
- EP ID EP242960
- DOI -
- Views 98
- Downloads 0
Role of Vesicular Trafficking in Infection and Cancer: A Review
Most of the pathogenic bacteria and viruses are capable of causing variety of infections in the respective hosts. These infectious agents enter and spread inside the host cells via various modes most notable of which is...
An Isolated Hydatid Cyst Of the Lung Spontaneously Evacuated into the Bronchus
Pulmonary hydatid cysts are common in endemic regions but isolated active pulmonary hydatid cyst, which is communicated with bronchus, is not a common finding in adult population. Here we present a case of 35-year-old ma...
PCR in tuberculosis: An extremely useful tool?
Introduction Tuberculosis is a global air borne infectious disease with significant increase in incidence and prevalence Conventional methods take longer time for diagnosis and drug susceptibility with less sensitivity a...
Microbiological profile of leucorrhoea in patients attending a tertiary care hospital at Jalna
Introduction and Objective: Leucorrhoea is an abnormal white, yellow or greenish vaginal discharge associated with irritation, is non-hemorrhagic in nature and signifies some underlying pelvic pathology. It is common com...
Seroprevalence of Chikungunya virus infection in Ballari and nearby districts of Karnataka
Background and Objective: Chikungunya virus (CHIKV) is an arthropod-borne virus, causes fever and nonspecific clinical manifestations similar to malaria and other bacterial infections, it is not routinely tested at the h...