A SYSTEMATIC REVIEW ON NATURAL MEDICINE USED FOR THERAPY OF DIABETES MELLITUS OF SOME INDIAN MEDICINAL PLANTS
Journal Title: Pharma Science Monitor-An International Journal Pharmaceutical Sciences - Year 2011, Vol 2, Issue 1
Abstract
Diabetes mellitus is one of the world’s major diseases. It currently affects an estimated 143 million people worldwide and the number is growing rapidly. In the India, about 1- 5% population suffer from diabetes or related complication. Plant-based medicinal products have been known since ancient times, and several medicinal plants and their products (active natural principles and crude extracts) have been used to control diabetes in the traditional medicinal systems of many cultures worldwide. Several medicinal plants have found potential use as hypoglycemic in the Indian system of medicines. Several oral hypoglycaemic agents are the primary forms of treatment for diabetes. However, prominent side-effects of such drugs are the main reason for an increasing number of people seeking alternative therapies that may have less severe or no sideeffects. In this review, we represent the profile of plants commonly used in India in the treatment of diabetes, reported in literature. A total of 45, 000 plant species have records of a popular use in the treatment of this syndrome in India. The profile presented includes information about scientific name, family, species, methodology used, the degree of hypoglycaemic activity and the active agents. Indian plants which are most effective and the most commonly studied in relation to diabetes and their complications are: Allium cepa, Allium sativum, Aloe vera, Beta vulgaris, Catharanthus roseus, Azadirachta indica, Gymnema sylvestre, Ipomoea batatas, Momordica cymbalaria,Momordica charantia, Ocimum sanctum, Pterocarpus marsupium, Swertia chirayita, Tinospora cordifolia, and Trigonella foenum graecum. All plants have shown varying degree of hypoglycemic and anti-hyperglycemic activity with different mechanism of action.
Authors and Affiliations
Donga J. J. , Surani V. S , Sailor G. U. , Chauhan S. P , Seth A. K.
Keywords
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