SIMULTANEOUS ESTIMATION OF NEBIVOLOL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE IN BULK AND IN A TABLET DOSAGE FORM BY MULTICOMPONENT AND SIMULTANEOUS ESTIMATION METHOD
Journal Title: Pharma Science Monitor-An International Journal Pharmaceutical Sciences - Year 2011, Vol 2, Issue 1
Abstract
Novel, simple, sensitive, rapid, accurate and economical spectrophotometric methods have been developed for simultaneous estimation of Nebivolol Hydrochloride and Hydrochlorothiazide. These methods involve solving of simultaneous equations based on measurement of absorbances at two wavelengths 290 nm and 317 nm. Both the drugs obey the Beer’s law in the concentration ranges employed for these methods. Results of the methods were validated statistically and by recovery studies.
Authors and Affiliations
K. V. Shah , P. R. Tirgar , D. B. Sheth , T. R. Desai
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