Accuracy of low dose CT in the diagnosis of appendicitis in childhood and comparison with USG and standard dose CT

Journal Title: Jornal de Pediatria - Year 2017, Vol 93, Issue 6

Abstract

Objectives Computed tomography should be performed after careful consideration due to radiation hazard, which is why interest in low dose CT has increased recently in acute appendicitis. Previous studies have been performed in adult and adolescents populations, but no studies have reported on the efficacy of using low-dose CT in children younger than 10 years. Methods Patients (n=475) younger than 10 years who were examined for acute appendicitis were recruited. Subjects were divided into three groups according to the examinations performed: low-dose CT, ultrasonography, and standard-dose CT. Subjects were categorized according to age and body mass index (BMI). Results Low-dose CT was a contributive tool in diagnosing appendicitis, and it was an adequate method, when compared with ultrasonography and standard-dose CT in terms of sensitivity (95.5% vs. 95.0% and 94.5%, p=0.794), specificity (94.9% vs. 80.0% and 98.8%, p=0.024), positive-predictive value (96.4% vs. 92.7% and 97.2%, p=0.019), and negative-predictive value (93.7% vs. 85.7% and 91.3%, p=0.890). Low-dose CT accurately diagnosed patients with a perforated appendix. Acute appendicitis was effectively diagnosed using low-dose CT in both early and middle childhood. BMI did not influence the accuracy of detecting acute appendicitis on low-dose CT. Conclusion Low-dose CT is effective and accurate for diagnosing acute appendicitis in childhood, as well as in adolescents and young adults. Additionally, low-dose CT was relatively accurate, irrespective of age or BMI, for detecting acute appendicitis. Therefore, low-dose CT is recommended for assessing children with suspected acute appendicitis.

Authors and Affiliations

In Seok Lim

Keywords

Related Articles

Accuracy of different cutoff points of body mass index to identify overweight according to body fat values estimated by DEXA

Objective To evaluate the sensitivity and specificity of different cutoff points of body mass index for predicting overweight/obesity according to body fat values estimated by DEXA among Brazilian adolescents. Methods C...

The time has come to invest more in the prevention of day care-associated infection in children

The shift from home-care to day care has had a significant impact on pediatric health and still remains a major risk factor for infections in toddlers and young children.1 The estimated risk is two to three times higher...

Suspected adverse drug reactions reported for Brazilian children: cross-sectional study

Objective To assess spontaneous reports of suspected adverse drug reactions in children aged 0–12 years from the Brazilian Health Regulatory Agency between 2008 and 2013. Methods A cross-sectional study on suspected adve...

Antibody persistence following meningococcal C conjugate vaccination in children and adolescents infected with human immunodeficiency virus

Objective HIV-infected individuals (HIVI) are threatened by meningococcal infection and presented lower response to vaccines. Data are scarce on long-term persistence of human serum bactericidal antibody (hSBA) after a m...

Newborn screening for sickle cell disease: necessary but not sufficient

Sickle cell disease is a global health problem that affects>300,000 newborns per year, predominantly in Sub-Saharan Africa,1 where mortality is estimated to be>50% by age 5 years for those with homozygous hemoglobin S (H...

Download PDF file
  • EP ID EP503185
  • DOI 10.1016/j.jped.2017.01.004
  • Views 71
  • Downloads 0

How To Cite

In Seok Lim (2017). Accuracy of low dose CT in the diagnosis of appendicitis in childhood and comparison with USG and standard dose CT. Jornal de Pediatria, 93(6), 625-631. https://europub.co.uk/articles/-A-503185