Acute pancreatitis leading to thrombotic thrombocytopenic purpura/haemolytic uremic syndrome (TTP/HUS) treated with therapeutic plasma exchange and haemodialysis- A Case Report
Journal Title: International Journal Of Research In Medicine - Year 2016, Vol 5, Issue 4
Abstract
BACKGROUND: Haemolytic uremic syndrome is a disorder in which there is acute kidney injury (AKI) with nonimmune haemolytic anaemia and thrombocytopenia. It is most commonly seen in children. There are very few cases reported where pancreatitis was the cause of TTP/HUS. We describe the case of a 30 year old male patient, who was admitted with diagnosis of acute pancreatitis (AP) and developed deterioration of renal function, despite fluid resuscitation. The clinical features, radiological findings and laboratory investigations were in favour of diagnosis of AP with TTP/HUS. Therapeutic plasma exchanges along with haemodialysis were started on alternate days. Renal failure was part of TTP/HUS in this patient with diagnosis of AP. The exact mechanism causing this condition is not clear. Early initiation of therapeutic plasma exchange has a major impact on survival and long term renal function improvement.
Authors and Affiliations
Bhargav Prajapati, Tarak Patel, Nidhi Bhatnagar, M. D. Gajjar, Shital Soni, Kaminidevi Gupta
Keywords
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