Adenoid cystic carcinoma of the head and neck — a 10 years experience
Journal Title: Otolaryngologia Polska - Year 2011, Vol 65, Issue 5
Abstract
SUMMARY Introduction: Adenoid cystic carcinoma (ACC) was first described in 1853 and 1854 by three french scientists, Robin, Lorain and Laboulbćne. ACC is a rare cancer of the head and neck (about 1%) and it comprises from 6% to 10% of alt malignant tumors of the salivary glands. 15%-30% of these tumors are located in submandibular gland, 30% occur in smali salivary glands (in the palate, tongue, mouth, nose, sinuses, mucous membrane of the cheeks) and about 6% in parotid gland. Because of its specificity ACC is a challenge for the doctor — it is usually recognized at an advanced stage, spreads along the nerves, it has a high propensity for recurrence, often gives distant metastases, 10-year survival are very smali. Aims: Aim of this study is the epidemiological and clinical analysis of patients with adenoid cystic carcinoma. Material and methods: Includes a retrospective analysis of 21 cases of patients with ACC of the head and neck were hospitalized at the ENT Clinic of the Warsaw Medical University between 2001 and 2011. Data from medical records contain information about the location of the tumor, symptoms and clinical signs, diagnos-tic methods, method of treatment and local recurrences and distant metastases. Results: most cases ACC occurred in the large salivary glands (14 cases), in 5 cases in the nasal cavity and maxillofacial region, in 2 cases in the tongue. In order to accurately determine the extent of the tumor, its relationship to adjacent structures was performed computed tomography and magnetic resonance imaging. Most of patients before treatment have been made biopsy of the tumor or download tissues by forceps for histopathological examina-tion. Reported symptoms depend on the location of the tumor. In 20 cases the patients were treated by surgical therapy and followed by radiotherapy, in one case because of the extent of the tumor was sent to radiotherapy. Conclusions:Surgical treatment of ACC requires a wide margin of healthy tissues; For the risk of local recurrences affected positive surgical margins, scull base Iocations of primary tumor and perineural invasion; Because of unpredictable nature of the tumor (local recurrences, distant metastasis), observation of patients after treatment should be carried out permanently, along with periodic imaging studies
Authors and Affiliations
Antoni Bruzgielewicz, Ewa Osuch-Wójcikiewicz, Daniel Majszyk, Piotr Chęciński, Jagna Nyckowska, Brygida Zawadzka, Anna Skowrońska-Gardas, Kazimierz Niemczyk
Keywords
Related Articles
- EP ID EP52347
- DOI -
- Views 85
- Downloads 0
Nd:YAG laser assisted uvulopalatoplasty in the treatment of obstructive sleep apnea syndrome
Introduction. Surgical treatment of OSAS is focused on removal of narrowing that increase airway resistance in upper respiratory tract. Nd:YAG laser beam penetrates deeper into tissue than CO2 laser followed by superior...
Wpływ wykonania kochleostomii na zachowanie słuchu – badania na modelu zwierzęcym
Introduction: To assess an effect of cochleostomy on hearing threshold in guinea pigs. Material and methods: The authors performed animal experiments using fi ve 3-month-old guinea pigs. Before experiment hearing thresho...
Rekonstrukcje ubytków nosa po operacjach onkologicznych w materiale Kliniki Otolaryngologii Warszawskiego Uniwersytetu Medycznego w latach 1998-2007
Introduction: Skin cancer (basal cell carcinoma, squamous cell carcinoma) and melanoma are the most frequent malignancy appearing in a human begin. The treatment of choice is surgical excision of tumor with margins of he...
Bezpieczne usunięcie AFJ po przedoperacyjnej obliteracji guza klejem tkankowym
The purpose of this work is to present the method of operating juvenile nasopharyngeal angiofi broma with the use of preoperative obliteration with tissue adhesive glue (Histoacryl). Authors described the case of 15 year...
Diagnostyka preimplantacyjna w kierunku niedosłuchu wrodzonego z mutacją 35deIG w genie GJB2 — doniesienie wstępne
SUMMARY Introduction: 35deIG mutation in GJB2 gene is the most frequent mutation in genetic hearing loss. The carrier screening for 35deIG mutation to identify affected newborns is at the moment relatively inexpensive me...