Adverse events in platelet-rich plasma collection and countermeasures

Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 11

Abstract

Objective To explore the quality of platelet-rich plasma(PRP) and adverse events during PRP collection and the countermeasures, so as to provide reference for the development of PRP therapy. Methods A total of 412 patients who underwent PRP treatment from November 2020 to October 2022 were statistically analyzed in terms of the general data, PRP quality and adverse events during collection, and the countermeasures were formulated. Results PRP was collected from 409 patients with a volume of (48.391±6.262) mL, with platelet concentration at (1 125.548±366.036)×109/L. There were 33 adverse events occurred in 412 patients, with an incidence of 8.01% (33/412), among which 10 was regarding to collection and 23 were adverse reaction to blood donation. The reasons include mental factors, hyperlipidemia, hypovolemia, abnormal red blood cell morphology and venous puncture injury. Conclusion Countermeasures against the relative risk factors of adverse events during PRP collection, such as exclusion of hyperlipidemia, relieving mental stress, providing adequate communication and water to patients with low body weight, lowering the collection and transfusion flow rate to patients with poor vascular status and providing calcium gluconate to patients with low calcium response should be taken.

Authors and Affiliations

Wenting WANG, Yan ZHENG, Ying LI, Shijie MU

Keywords

Related Articles

Clinical application progress of platelet-rich plasma in facial aesthetics

Platelet-rich plasma (PRP) is a kind of autologous blood product. It is a platelet concentrate extracted from autologous blood through centrifugation or apheresis process. It is generally believed that the platelet conce...

The challenge of finding Chinese blood groups

Up to now, hundreds of human blood groups have been detected globally, but none have been found in the Chinese population. China is a multi-ethnic country with rich genetic polymorphism and variation. The Chinese pangeno...

Diagnostic analysis and clinical treatment strategies for patients with hyperhemolytic syndrome: a case report

Objective To analyze a case of hyperhemolytic syndrome(HHS) and explore the laboratory diagnostic method and clinical treatment strategy. Methods Serological tests such as blood typing, direct antiglobulin test(DAT), ant...

Perioperative allogenic blood transfusion for single disease in patients undergoing spinal deformity correction surgery:a longitudinal observational study

Objective To analyze the profile of perioperative allogenic blood transfusion for single disease in patients who underwent spinal deformity correction surgery and risk factors of the blood transfusion, in order to provid...

Desalination effect on FⅧ components: a compartive study among 5 desalination methods

Objective To compare the desalination effects of five desalination methods and their effects on the components for human coagulation factor Ⅷ(FⅧ), and provide reference for selection of protein desalination methods. Meth...

Download PDF file
  • EP ID EP738694
  • DOI 10.13303/j.cjbt.issn.1004-549x.2023.11.014
  • Views 36
  • Downloads 0

How To Cite

Wenting WANG, Yan ZHENG, Ying LI, Shijie MU (2023). Adverse events in platelet-rich plasma collection and countermeasures. Chinese Journal of Blood Transfusion, 36(11), -. https://europub.co.uk/articles/-A-738694