Ameloblastoma and its Malignant Transformation: Treatment Ladder, Related Syndromes and Controversies
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 2
Abstract
Odontogenic Tumour is a term that encompasses a wide spectrum of lesions ranging from malignant and benign neoplasms, all arising from odontogenic apparatus. Distinction among the tumours may, in part depend on the embryologic stage of initiation and the histologic and gross appearance of the lesion at the age of clinical discovery. Ameloblastomas are known to occur at unusual locations, metastasize, or transform into malignant neoplasms. They may show various biologic behaviours, ranging from cystic expansion to more aggressive infiltration of adjacent tissue. Ameloblastomas have a wide variation in clinical presentation, histology and prognosis, and they are also known for late recurrences, significant local morbidity and systemic spread. Though many advances are being made in the diagnosis and management of this tumour, there always has existed an air of debate and controversy on the very nature and management of this tumour. Various authors have different viewpoints regarding the nature of this tumour due to its myriad presentations. Newer treatment modalities have been tried over the years to prevent recurrence, reduce morbidity and facilitate adequate rehabilitation in patients affected with ameloblastoma.
Authors and Affiliations
Anshuman Kumar, Aviral Verma, Apala Baduni, Navneet Kaur
Keywords
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