An analysis of cervical pap smear cytology as a screening procedure in a rural tertiary care hospital
Journal Title: Medpulse International Journal of Pathology - Year 2019, Vol 10, Issue 1
Abstract
Background: Cancer of cervix is the second most common cancer in women in world and one of the leading malignancies seen in Indian women. Cancer of cervix is preventable if diagnosed at the pre-invasive stage with regular intervals of cytological screening by Papanicolaou (PAP) smears. Aims and Objectives: The objective of the study is to evaluate the entire spectrum of types and frequencies of cervical cytological abnormalities on PAP smear according to Bethesda system and to correlate cytology with histopathology wherever possible. Materials and Methods: This is a prospective study conducted at a rural tertiary care centre in Department of pathology from April 2018 to March 2019. After doing Pap stain, conventional pap smears were reported adopting Bethesda system. Results: A total of 3360 cases of pap smears were received. Most women were in the age range of 30–40 years. White per vaginal discharge was the most common complaint, occurring in 20.23% of the women. White discharge was the most commonly noted per speculum abnormal finding (16.76% cases). 90% cases were negative for intraepithelial lesion or malignancy (NILM), 4% showed epithelial cell abnormalities (ECA) and 6% were inadequate. In NILM category, inflammatory/reactive changes were commonest. Bacterial vaginosis was commonest infective etiology. In ECA category, Atypical squamous cells of undetermined significance was most common followed by low‑grade squamous intraepithelial lesion. Overall ECA was common in 31-50 years age group. In the present study overall sensitivity was 87.5%, specificity 98.9%, positive predictive value 94.9%, negative predictive value 97.1%, diagnostic accuracy 96.7%. Conclusion: Pap smear examination is an effective screening and diagnostic procedure for the detection of premalignant and malignant cervical lesions at an early stage. It is also helpful in identifying the infectious etiologies and treatment in developing countries. Thereby helping the clinicians in more efficient management of the patients. Key Word: https://doi.org/
Authors and Affiliations
Neha Mukesh Goel
Keywords
Related Articles
- EP ID EP591035
- DOI 10.26611/1051017
- Views 55
- Downloads 0
Pathological profile of soft tissue tumours: - A descriptive study
Soft tissue Tumours are classified according to their histogenetic origin and within each group they are divided into benign lesions, intermediate lesions and sarcomas.1The grade of malignant Tumours is the single most e...
Quality control of whole blood and blood components - Good quality measure for efficient supply of blood products
Background: Quality Control describes steps taken by Blood Bank to ensure that tests are performed correctly. Primary goal of Quality Control is Transfusion of safe quality of blood. It is to ensure availability of effic...
Spectrum of bone marrow aspiration and biopsy findings in cases of pancytopenia
Background: Pancytopenia is a manifestation of many underlying disease conditions which can be life threatening if not treated promptly. This study was conducted to evaluate the etiological, clinical and hematological fe...
Clinicopathological spectrum of female genital tract neoplasms - A rural tertiary care hospital study
Background: On a worldwide basis, the most common gynecological neoplasm in women is cervical cancer, second only to breast cancer as the most common cancer of women. Present study focuses on neoplastic lesions in endome...
Adenomatoid tumour with leiomyomatous component: A rare entity
Background: Adenomatoid tumors are regarded as distinctive benign mesothelial neoplasms of the paratesticular region, most commonly occurring at the tail of the epididymis. A variant with leiomyomatous component is even...