An association between typhoid fever and Age, Sex and Blood Phenotypes ABO and Rh among Children – a Study in a Tertiary Care Hospital, Dhaka, Bangladesh
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 9
Abstract
A case-control type of study was conducted over a period of 6 (Six) months following approval in the Department of Paediatric of Dhaka Shishu Hospital, Dhakato assess the association the association betweenTyphoid fever and age, sex and blood phenotypes ABO and Rh among children. The sample size for this study was 240 (120 cases and 120 controls). Out of 120 participants in each group 79.2% cases and 68.3% controls respondents were mother of the children. In both groups most of the study participants were from younger age group ≤ 5 years; 63.3% of cases and 80.8% of control. Mean ± SD of age were (5.1042 ± 3.11575) for cases and (3.5951 ± 2.50218) for controls Age distribution of the children was statisticallysignificant where p -value was 0.0001 for t-test and 0.01151045 for chi-square (p<0.05).Most of the children were urban dwellers 89.2% cases and 96.7% controls. The difference was statistically significant (χ2 = 4.134, p = 0.04202989) and 35.0% of cases drunk supply water in comparison with only 13.3% of controls. There was positive association of drinking supply water with typhoid fever (RR=2.6316 and OR=3.5101 and χ 2 =12.85; p-value = 0.000337). Crowdie habitat was reported by 38.3% of Cases and 10.8% of Controls. There may be strong association of crowdie condition of habitat with typhoid fever (RR = 3.5463; OR = 5.1269 and χ2 = 20.41; p =0.0001). There was no positive association of different blood group but when each group was individually considered, blood group ‘B’ indicated there may be some positive association (RR = 1.4505, OR = 1.8713 and χ2 = 4.66, p = 0.030873). Only 3.3% children in case group and 4.2% in control group had Rh negative blood group. Widal test result was positive in 83.3% of cases; the remaining 16.7% were found to be Widal negative. The difference was statistically significant (χ2 = 18.22, p =0.0001. Blood culture was done in only 50 (41.7%) participant from the case group; out of them negative culture was obtained in 4 individuals, the difference was statistically significant (χ2 = 52.585, p = 0. (P< 0.05). Typhoid fever has a strong relation with socio-economic conditions and blood phenotypes.
Authors and Affiliations
Dr. Amal Kanti Banik, Dr. ATM Nurul Kabir, Dr. Jahangir Alam
Keywords
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- EP ID EP395423
- DOI 10.9790/0853-1709086369.
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