An Experience with Lung-Protective Mechanical Ventilation in ARDS Patients in Intensive Care Unit: Survivors vs Non-Survivors
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 8
Abstract
Introduction: ARDS i.e Acute respiratory distress syndrome is a serious clinical condition, often fatal, in which acute hypoxaemic respiratory failure occurs due to direct or/and indirect lung injury by various factors. Positive pressure mechanical ventilation is the key therapy to combat this dreaded condition in present day scenario. Study was aimed at observing the clinical profile and outcome of the ards patients on lung protective mechanical ventilation with a vis-a-vis comparison of survivors versus non-survivors of ARDS. Material and Methods: This was a prospective observational study and conducted over a duration of one year in Emergency departmental ICU of a tertiary –care Government medical college hospital in India to have a comparative analysis of various clinical profiles of survivors and non-survivors of ARDS, undergoing lung protective mechanical ventilation protocol laid down by ARDS Network. Results: Clinical profiles of 44 ARDS patients, satisfying Berlin Definition of ARDS, 2012 were studied. Mortality was 54.54% where sepsis was the prime etiological factor. Nonsurvivors had higher initial Plateau Pressure as well as PaO2/FiO2. Requirement of PEEP and FiO2 were also significantly higher among non-survivors. Conclusions: Lung protective mechanical ventilation strategy with treatment of precipitating factors still remains the treatment of choice to improve the survival and reducing morbidities in ARDS patients.
Authors and Affiliations
Deepak Chaudhury, Lakshimi Borgohain, Subhankar Paul, Jehbi Hasan, Ilias Ali
Keywords
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