An observational study of use of steroid in acute liver injury caused by hepatitis E virus in a tertiary care hospital in kolkata - a therapeutic challenge
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Hepatitis E virus is one of the leading causes of acute liver failure in clinical situation especially in immune-compromised patients , it has a high incidence in Asian countries and many people died due to lack of proper treatment . In this study , steroid (prednisolone ) was used as therapeutic challenge in such patients and significant improvement in clinical and biochemical parameters were found ( SGPT , prothrombin time and total bilirubin ) . This observational study highlights the possibility of steroid treatment as a therapeutic rescue in patients with hepatitis E. Further studies are required to evaluate whether steroid treatment has a supportive role for patients with HEV induced acute liver injury and improves their spontaneous outcome
Authors and Affiliations
Raja Bhattacharya, Ritasman Baisya, Urmimala Bhattacharjee (2) ,, Pallab Biswas, Akashdip Bhattacharya (2)
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