An Observational Study on Association of Helicobacter Pylori in Patients with Gastric Carcinoma.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 12
Abstract
Background: Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's population. Infection with H. pylori causes chronic inflammation and significantly increases the risk of developing duodenal and gastric ulcer disease and gastric cancer. Methods: Hospital based prospective study conducted at Department of general surgery, Calcutta National Medical College and Hospital, Kolkata. Patients aged over 35 years undergoing endoscopic biopsy evaluation for Ca-stomach & those who are being operated for Ca-stomach were included in this study. Results: H. pylori is the gastric pathogen and it causes chronic inflammation which ultimately increases the risk of gastric cancer. In our study 31/35(88.57%) patients out of total 35 patients of carcinoma stomach were having H.pylori infection(i.e. RUT-positive cases). Only 4/35 cases of carcinoma stomach were found RUT-negative. Conclusion: Helicobacter pylori is the common pathogen cause gastric carcinoma.
Authors and Affiliations
Mahendra Kumar
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