Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

Journal Title: Strojnicky casopis - Journal of Mechanical Engineering - Year 2016, Vol 66, Issue 1

Abstract

This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel, Kawakita, Cooper-Eaton and Adams compaction equations. Experimental material was determined by measuring its parameters as particle size distribution, angle of wall friction and flow properties and for more detailed characteristics of the material particles, microscopy images of the powder before and after compressing were created.

Authors and Affiliations

Peter Peciar, Maroš Eckert, Roman Fekete and Viliam Hrnčiar

Keywords

Related Articles

Static Characteristics of Pressure Control Valve

The article deals with the measurement of static characteristics of a pressure control valve. The pressure, at which the valve starts to leak oil, is adjusted by a spring. The measurement is performed on a hydraulic sy...

nfluence of Induction Hardening on Wear Resistance in Case of Rolling Contact

The main aim of the presented paper is to show how heat treatment, in our case the induction hardening, will affect the wear rates as well as the ratcheting evolution process beneath the contact surface in the field of...

Buckling Analysis of Hetero-Junction Carbon Nanotubes

The buckling analysis of carbon nanotubes without and with hetero-junctions is described in this paper. The buckling behaviour was investigated by the finite element method and the carbon nanotubes were modelled as spa...

Evaluation of Fracture Parameters for Cracks in Coupled Thermoelasticity for Functionally Graded Materials

The finite element method (FEM) is developed for coupled thermoelastic crack problems if material properties are continuously varying. The weak form is utilized to derive the FEM equations. In conventional fracture the...

FSW Numerical Simulation of Aluminium Plates by SYSWELD - Part II

Friction Stir Welding (FSW) is one of the most effective solid state joining processes and has numerous potential applications in many industries. The simulation process can provide the evolution of physicals quantitie...

Download PDF file
  • EP ID EP43884
  • DOI https://doi.org/10.1515/scjme-2016-0012
  • Views 297
  • Downloads 0

How To Cite

Peter Peciar, Maroš Eckert, Roman Fekete and Viliam Hrnčiar (2016). Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations. Strojnicky casopis - Journal of Mechanical Engineering, 66(1), -. https://europub.co.uk/articles/-A-43884