Analysis of the current trend in the prescription of anti-hypertensive drugs among pregnant females in a tertiary care hospital
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2014, Vol 3, Issue 4
Abstract
Background Hypertensive disorders are the leading cause of maternal and perinatal mortality and morbidity in India and worldwide, as it is among the most common of all medical complications in pregnancy. Material & Methods A single centric, observational, cross-sectional, non-randomized study conducted in the department of pharmacology in collaboration with Antenatal care (ANC) Outpatient department of Obstetrics & Gynecology. Results Among the 116 hypertensive patients, 108 patients participated in the study. Age distribution showed majority of the participants, 101 (93.51%) were in the reproductive age group i.e. 20-35 years. Trimester wise distribution of the participants showed more than half of the participants, 57 (52.77%) were in third trimester of their term. 62 (57.40%) participants were diagnosed as mild hypertensive and 46 (42.59%) as severe. Gestational hypertension was the most common of all the hypertensive disorder among the study participant. Majority of the patients, 73(67.59%), were preferred for monotherapy. Beta blocker was the preferred class as a monotherapy among the pregnant females followed by centrally acting anti-hypertensive drugs. Labetolol was the preferred antihypertensive followed by centrally acting Methyl dopa. Combination of two antihypertensive drugs was given to 12 participants and combination of anti hypertensive along with anticonvulsants was preferred in 23 participants. Combination of two drugs was used in 19 (17.59%) participants and combination of three drugs was used in 16 (14.81%) participants in the treatment of hypertension. Conclusion: Hypertension is one of the most common problems encountered in pregnancy. Monotherapy was preferred as a treatment of choice and future study should include detailed outcomes of risk and benefit for both the mother and baby.
Authors and Affiliations
Sagar B Bhagat
Keywords
Related Articles
- EP ID EP412848
- DOI -
- Views 110
- Downloads 0
Evaluation of hypoglycaemic activity of shilajit in alloxan induced diabetic rats
Background Diabetes mellitus is a potentially morbid condition with high prevalence worldwide. This disease constitutes a major health concern affecting about 2.8% of the global population. Currently available synthetic...
Anti-obesity and anticoagulant activity of ethanol extract of Trigonella foenum-graecum L
Aim To study the antiobesity and anticoagulant activity of ethanol extract of Trigonella foenum-graecum L. (Fenugreek) in male wistar rats. Methods Trigonella foenum-graecum L. was first extracted with ethanol and subje...
Effect of melatonin on body weight, plasma lipid, leptin and insulin levels in high fat diet fed rats
Aims and Objectives To understand the influence of melatonin on body weight, plasma lipid, leptin and plasma insulin levels. Materials and Methods A total of 36 laboratory bred male Sprague dawley rats were used for the...
Evaluation of Cardiotonic and Cardioprotective Effects of Paederia foetida.
Aim of the study The present study is undertaken to study the cardiotonic activity and its protective role on heart by Paederia foetida belonging to the family Rubiaceae. Materials and Methods Paederia foetida leaf extr...
Pattern of drug prescriptions in pediatrics ward of university of gondar specialized hospital, gondar, ethiopia
Introduction: The assessment of prescribing pattern in pediatrics has an important relevance to identify problems regarding rational uses of drugs and to propose intervention. The objective of this study was to evaluate...