Analysis of the Lipid Profile, Fasting Glucose Levels, and Their Familial Dependence in Warsaw Adolescents
Journal Title: Postępy Nauk Medycznych - Year 2013, Vol 26, Issue 11
Abstract
Introduction. Abnormal lipid profile and altered glucose metabolism are considered to be risk factors for cardio-metabolic diseases in adults. However, the processes leading to the onset of these diseases often have their origins in childhood. A tendency to develop certain disorders can be inherited.Aim. The purpose of this study was to analyze the lipid profiles and glucose levels among young people in Warsaw, and to determine whether the tested values correlated with the occurrence of cardio-metabolic diseases in their immediate family.Material and methods. The studied group consisted of 309 adolescents representative for the population of high-school students in Warsaw. Participants and their parents were required to provide information regarding the occurrence of obesity, diabetes, hypertension, hyperlipidemy and cardio-vascular diseases in their close families. Fasting glucose, triglycerides, total cholesterol, HDL and LDL levels were measured.Results. All the above mentioned family factors occurred frequently. The most common were hypertension and ischemic heart disease. Abnormal LDL and HDL levels were the most often occurring abnormalities. Correlations was noted between the total cholesterol in the participant and both the occurrence of hyperlipidemia in the family, and the total count of all family factors.Conclusions. Lipid and glucose metabolism disorders are not unique in young people. Although their prevalence is under a strong influence of dietary and lifestyle factors, certain tendencies depend on the occurrence of cardio-metabolic disorders among relatives. Study suggests, that the closer monitoring is need for children with history of cardio-metabolic diseases in close family.
Authors and Affiliations
Jarosław Kozakowski, Andrzej Kulesz, Aleksandra Wycisk, Wojciech Zgliczyński
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