Anthelmintic activity of seed extracts of Artocarpusheterophyllus
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 5
Abstract
Helminthic infections are now being recognized as cause of many acute as well as chronic ill healthamong the various human beings as well as cattle’s. Helminthiasis, the condition resulting from worm infestation, is one of the major prevalent diseases in the world, particularly in the tropical countries. Lack of adequate sanitary facilities and supply of pure water coupled with poverty and illiteracy are some of the factors responsible for wide spread nature of this disease in the developing countries. The present study aimed at the in-vitro evaluation of anthelmintic activity of ethanol, ethyl acetate and aqueous extracts of seeds of the plant “Artocarpusheterophyllus” in earthworms (Pheretimaposthuma). The test samples were given in the dose of 25mg/ml, 50mg/ml, and 100mg/ml. The ethyl acetate extract showed more significant activity when compared to ethanol and aqueous extracts of seed. Whereas ethanol and aqueous extracts has showed moderate anthelmintic activity at prefixed time. Since detailed investigation of anthelmintic activity has not been carried out so far, present study was under taken.
Authors and Affiliations
Yashaswini . T, Akshara 1, A. M. Krupanidhi2, Prasad K3 ,, Kumar M. D, Akshaykumar K5
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