Anti-inflammatory and Analgesic activity of mature leaves methanol extract of Clerodendrum inerme L. (Gaertn)
Journal Title: Journal of Pharmaceutical Sciences and Research - Year 2010, Vol 2, Issue 11
Abstract
Clerodendrum inerme is a hedge plant belongs to the Verbenaceae family, traditionally used for ornamental purpose in home gardens. In the present study, anti-inflammatory and analgesic effect of methanol extract of Clerodendrum inerme (MECI) was evaluated in animal models. The anti-inflammatory activity of MECI exhibited sub-chronic (cotton pellet-induced granuloma) models of inflammation was found to be significant. In addition, the extract also showed significant analgesic activity in acetic acid induced writhing. Therefore, the anti-inflammatory and analgesic activity observed in the present study with MECI could be attributed largely to its antioxidant and lysosomal membrane stabilizing effects.
Authors and Affiliations
Yankanchi S. R , Koli S. A
Keywords
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