Synthesis and Characterization of 2,6-Dihydroxy Substituted Chalcones Using PEG-400 as a Recyclable Solvent
Journal Title: Journal of Pharmaceutical Sciences and Research - Year 2010, Vol 2, Issue 8
Abstract
A novel method for the synthesis of 2,6-dihydroxy substituted chalcones via Claisen-Schmidt is introduced using recyclable PEG-400 as an alternative reaction solvent. The reaction is clean with excellent yield, shorter reaction time and reduces the use of volatile organic compounds (VOCs). The structures of the synthesized compounds were confirmed by IR, mass spectroscopy and elemental analysis
Authors and Affiliations
M. R. Jayapal , K. Sreenivasa Prasad , N. Y. Sreedhar
Keywords
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