Anti-Obesity Effect of a Mixture of Skim Milk, Red Ginseng Extract, and Black Raspberry Extract Fermented with Lactobacillus acidophilus on High-Fat Diet-Fed Obese Mice
Journal Title: Journal of Food Chemistry and Nanotechnology - Year 2016, Vol 2, Issue 2
Abstract
The aim of this study was to assess the anti-obesity effect of Lactobacillus acidophilus-fermented mixture of skim milk, red ginseng extract, and immature fruit of Rubus coreanus Miquel (called black raspberry) extract in a mouse model of diet-induced obesity. Male C57BL/6J mice were fed a normal diet (ND), high-fat diet (HFD), high-fat diet supplemented with fermented skim milk (HFD-FSM), or high-fat diet supplemented with the fermented mixture (HFDFMIX). FSM and FMIX were orally administered (2 g/kg of body weight) on a daily basis. Following a 6-week regimen, the following physical and biochemical measures were assessed: feed intake, body weight, periepididymal fat and perirenal fat mass, size of the epididymal adipocytes, and plasma levels of glucose, insulin, adiponectin, and leptin. No significant differences were observed in all parameters tested in the HFD-fed and HFD-FSM-fed groups, except the plasma leptin level, which was higher in the HFD-FSM-fed group than in the HFD-fed group. In the HFD-FMIX-fed group, feed intake was similar to, but the adiponectin level was higher than that in the HFD-fed group. The HFD-FMIX-fed group showed significantly lower increase in body weight, size of epididymal adipocytes, and plasma levels of glucose and leptin than the HFD-fed group. These results demonstrate that the obesity-related measures can be decreased in obese mice by administration of L. acidophilus-fermented mixture of skim milk, red ginseng, and black raspberry fruit extract. These results also suggest that the fermented mixture can possibly be utilized as a functional food material with an anti-obesity effect.
Authors and Affiliations
Eun Ji Yum, Nam Keun Lee, Jisun Oh, Chang Hyun Lee, Mi Jin Oh, Ha-Rim Kim, Chan-Ho Oh, Jong-Hyuk Park, Hye-Jung Moon, Yong-Seob Jeong
Keywords
Related Articles
- EP ID EP223188
- DOI 10.17756/jfcn.2016-012
- Views 154
- Downloads 0
Oil, Protein, Chlorophyll, Cadmium and Lead Contents of Seeds in Oil and Fiber Flax (Linum usitatissimum L.) Cultivars and in Oil Hemp (Cannabis sativa L.) Cultivar Finola Cultivated in South-Western Part of Finland
Chemical composition of seeds of two minor oil crops, flax (Linum usitatissimum L.) and oil hemp (Cannabis sativa L.) cultivated in Finland were analyzed and compared to others. Oilseed flax cultivars were Abacus, Aries,...
Effects of Surface Charge on the Fate and Phytotoxicity of Gold Nanoparticles to Phaseolus vulgaris
Rapid advancement of nanotechnology has caused serious concerns over the potential release and accumulation of engineered nanoparticles (ENPs) in the environment. Gold nanoparticles (AuNPs) in particular, has attracted s...
Biosynthesis of Gold Nanoparticles by Biotechnologically Important Active and Inactive Form of the Ascomycetes - Pichia membranifaciens and Debaryomyces hansenii
The two biotechnologically important Ascomycetes, Pichia membranifaciens and Debaryomyces hansenii, were tested (in active and inactive form), in the present study for efficient bioreduction of trivalent aurum to gold na...
Improved Functionality of Foamed WPI Solutions by Ultrasound Application
The objective of this work was to determine the effect of ultrasound on the stability of foams of whey protein isolate. It was used an ultrasonic processor Vibra Cell Sonics, model VCX at a frequency of 20 kHz and an amp...
Anti-Diabetic Effects of Leaves of Trigonella foenumgraecum L. (Fenugreek): Leads from Preclinical Studies
Diabetes mellitus, a metabolic disorder of the endocrine system is one of the World’s oldest diseases known to man. Since time immemorial plants have been used as anti-diabetic agents in the various traditional systems o...