Anti-stress effects of cinnamon (Cassia zelynicum) bark extract in cold restraint stress rat model
Journal Title: International Journal of Research and Development in Pharmacy & Life Sciences (IJRDPL) - Year 2012, Vol 1, Issue 1
Abstract
The present study aims at investigating the anti-stress effects of cinnamon (Cassia zelynicum) bark extract in cold restrained stress (CRS) model. The cinnamon anti-stress effect was characterized using ulcer scoring, adrenal-gland weight, estimation of plasma glucose and cholesterol levels, as well as estimation of norepinephrine (NE) and corticosterone. Our results demonstrated that cinnamon is effective in minimizing stress responses by alleviating the increased level of ulcer scoring, plasma corticosterone, NE, glucose and total cholesterol levels which was induced in rats subjected to CRS. Thus, cinnamon is found to be effective in minimizing stress responses at a dose of 200 mg/kg thereby beneficial in stress therapy.
Authors and Affiliations
Bhagawati Saxena| Pharmacology Research laboratory, Department of Pharmaceutics, Meerut Institute of Engineering and Technology, Meerut, India, Urmila Saxena| Department of Biotechnology, Indian Institute of Technology Guwahati, Guwahati, India
Keywords
Related Articles
- EP ID EP15974
- DOI -
- Views 474
- Downloads 40
Antioxidant properties of polyphenolic rich HPLC standardized extract of Beta vulgaris L. roots
OBJECTIVES: The present study was planned to evaluate the antioxidant effects of standardized Beta vulgaris L. or beetroot. METHODS: The polyphenols present in lyophilized water extract of beetroot (BR) were quantifie...
Preparation of Sustained Release Microspheres of Aceclofenac: Characterization&in-vivostudies
Objective: To explore the sustained drug release model of Aceclofenac from microspheres to establish the result of hydrogel forming mucoadhesive polymers on drug release. Methods: Microspheres were produced by Emulsio...
Effect of Yogic exercise on static Spirometery values in normal healthy individuals
Introduction: Yogic practices can be a very good exercise for maintaining proper health and has a profound effect on the lung functions of an individual. They are also used as psycho-physiological stimuli to increase t...
EUDRAGIT-BASED NANOSTRUCTURES: A POTENTIAL APPROACH FOR OCULAR DRUG DELIVERY
Drug delivery in ocular therapeutics is a challenging problem and is a subject of interest to scientists working in the multidisciplinary areas pertaining to the eye. Most ocular diseases are treated by topical drug app...
Inhibition of Pro-Inflammatory Cytokine TNF-α by Boerhaavia diffusa (L.) in Liposaccharide stimulated Human THP-1 cells
The production and release of proinflammatory cytokines such as Tumor necrotic factor-α (TNF- α), Interleukin-1β and Iinterleukin-6 from monocytes/macrophages play critical role in the pathogenesis of chronic inflam...