Anti-stress effects of cinnamon (Cassia zelynicum) bark extract in cold restraint stress rat model
Journal Title: International Journal of Research and Development in Pharmacy & Life Sciences (IJRDPL) - Year 2012, Vol 1, Issue 1
Abstract
The present study aims at investigating the anti-stress effects of cinnamon (Cassia zelynicum) bark extract in cold restrained stress (CRS) model. The cinnamon anti-stress effect was characterized using ulcer scoring, adrenal-gland weight, estimation of plasma glucose and cholesterol levels, as well as estimation of norepinephrine (NE) and corticosterone. Our results demonstrated that cinnamon is effective in minimizing stress responses by alleviating the increased level of ulcer scoring, plasma corticosterone, NE, glucose and total cholesterol levels which was induced in rats subjected to CRS. Thus, cinnamon is found to be effective in minimizing stress responses at a dose of 200 mg/kg thereby beneficial in stress therapy.
Authors and Affiliations
Bhagawati Saxena| Pharmacology Research laboratory, Department of Pharmaceutics, Meerut Institute of Engineering and Technology, Meerut, India, Urmila Saxena| Department of Biotechnology, Indian Institute of Technology Guwahati, Guwahati, India
Keywords
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- EP ID EP15974
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