ANTI-ULCER ACTIVITY OF RASA PARPATI IN RATS
Journal Title: PARIPEX-Indian Journal of Research - Year 2019, Vol 8, Issue 6
Abstract
Rasa Parpati is one of the mineral formulation indicated mainly in Gastro Intestinal disorders. In the present study, the Anti ulcer activity of Rasa Parpati was studied by calculating the total number of ulcers, Ulcer index, its Percentage of inhibition, histological study and by the estimation of catalase, GSH, and lipid peroxidation. Rasa parpati have shown significant decrease in the number of ulcers and ulcer index and significant increase in % inhibition of ulcers as compared with control group. Histological studies revealed that ulcer control group exhibited severe damage of gastric mucosa, compared to rats pre-treated with Rasa parpati. Significant increase was observed in the levels of the antioxidant defense enzyme glutathione(GSH) in the gastric mucosa, whereas that of a lipid peroxidation was significantly decreased in rats pre-treated with Rasa parpati. Results indicate that Rasa parpati possess significant Anti ulcer property.
Authors and Affiliations
Dr. Anuroopa H K, Dr. Suman Suman
Keywords
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