ANTIBACTERIAL, ANTIFUNGAL AND ANTIOXIDANT ACTIVITIES OF TUNISIAN OLEA EUROPAEA SSP. OLEASTER FRUIT PULP AND ITS ESSENTIAL FATTY ACIDS
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2015, Vol 7, Issue 1
Abstract
Objective: This study was conceived to evaluate the essential fatty acids, secondary metabolite, antimicrobial and antioxidant activities of Olea europaea ssp. oleaster fruits pulp methanolic extract.Methods: Analysis of the lipid content from unexploited Olea europaea ssp. oleaster pulp was carried out using gas chromatography. The antioxidant activity was evaluated by DPPH radical scavenging. The antimicrobial activity was also tested against seven pathogenic bacteria, two fungal species and one yeast strain using two methods.Results: The obtained results showed that the major components of fatty acids were oleic acid (77.4%) and elaidic acid (17.58%). Moreover, the tested extract was rich in phenol (84.04±0.01 mg GAE/g DW) than in flavonoids (60.41±0.02 mg RE/g DW). In addition, it showed puissant antioxidant (IC50 = 28±0.01 µg/mL), antibacterial and antifungal activities. The inhibition zones diameters and the minimum inhibition concentration values for tested microorganisms were in the range of 13-18 mm and 3.125-25 mg/mL, respectively.Conclusion: This study shows that Olea europaea ssp. oleaster fruit pulp could be developed into ingredients for use in foods as the natural antioxidant and antimicrobial agent.
Authors and Affiliations
Ghazghazi Hanene, Chedia Aouadhi, Safa Hamrouni, Wissem Mnif
Keywords
Related Articles
- EP ID EP579156
- DOI -
- Views 41
- Downloads 0
INSILICO EVALUATION OF ANTISMOKING ACTIVITY OF ERYTHRININE: A COMPUTATIONAL COMPARISON AGAINST CYTISINE
Objectives: Erythrinine is a new ring-C-oxygenated Erythrina alkaloid from plant sources Erythrina Indica. The aim of this study is to investigate the smoking cessation activity of Erythrinine and its analogues using i...
CLINICAL PHARMACIST’S INTERVENTIONS ON DRUG RELATED PROBLEMS IN A TERTIARY CARE HOSPITAL
Objective: To identify various drug related problems in patients admitted to the general ward of a tertiary care hospital and to make suitable drug therapy recommendations.Methods: A prospective observational study was c...
EFFECT OF ORLISTAT ON LEARNING AND MEMORY IN NORMAL AND MEMORY DEFICIT ANIMALS
Objective: To investigate the possible effect of Orlistat on learning and memory in normal and memory deficit animals in two different age groups of mice.Methods: The effect of Orlistat on learning and memory was evaluat...
UTILIZATION OF ALCOHOLIC BEVERAGE DISTILLERAY WASTE WATER FOR PRODUCTION OF DOCOSAHEXAENOIC ACID
Objective: The marine thaustochytrid Schizochytrium sp known to produce docosahexaenoic acid (DHA), a polyunsaturated fatty acid with food and pharmaceutical applications. In the present study, distillery waste was studi...
ASSESSMENT OF GESTATIONAL DIABETES MELLITUS RELATED STRESS USING A SPECIFIC SCALE ADMINISTERED AS AN ONLINE MOBILE APPLICATION
Objective: Aim of the study was to assess the Gestational Diabetes Mellitus (GDM) related stress among pregnant women using an online mobile application based specific stress scale for GDM. Methods: This was a prospecti...