Antibiogram of the Prevalent Uropathogens Isolated at a Tertiary Care Hospital
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 2
Abstract
Introduction: Urinary tract infections (UTIs) are among the most common bacterial infection encountered. As there is emergence of resistance in the uropathogens to multiple drugs, a local study regarding the sensitivity pattern of common uropathogens is necessary. Aims and Objectives: This study was aimed at analyzing the antimicrobial susceptibility pattern of prevalent uropathogens, isolated in UTI patients at Tertiary care hospital, RIMS, Ranchi. Materials and Methods: This study was performed in the Department of Microbiology, RIMS, Ranchi. The pathogens in urine samples were identified by standard microbiological techniques and their antibiogram was determined by Kirby-Bauer disc diffusion method as recommended in CLSI, 2017. Results: Out of 2571 samples, 561 were culture positive. Among all uropathogens; Escherichia coli 169 (30.17%) was found to be the commonest organism, followed by Klebsiella species 157 (28.03%) and pseudomonas species 69 (12.32%). Escherichia coli was found sensitive to imipenem (90.53%) followed by amikacin (79.28%), levofloxacin (71.59%), gentamicin (60.35%). Klebsiella species shows high sensitivity to imipenem (88.53%), cefoperazone with sulbactam (72.61%), gentamicin (70.06%) and amikacin (57.96%). Pseudomonas the third most predominant isolate gave high sensitivity to piperaciillin-tazobactam (89.85%), imipenem (84.05%) and amikacin (65.77%). Conclusion: Overenthusiastic use of antibiotic has resulted in emergence of drug resistant bacterial strains in UTI patients. Hence, antibiotic susceptibility testing is essential and aids to diagnose and treat the drug resistant UTI cases.
Authors and Affiliations
Manoj Kumar, Manish Kumar Sinha, Ashok Kumar Sharma, Amber Prasad, Ashwini Verma
Keywords
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- EP ID EP540096
- DOI 10.21276/ijmrp.2018.4.2.071
- Views 78
- Downloads 0
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