Antimicrobial activity of aqueous and methanol extract of naturally growing and cultivated Aloe turkanensis
Journal Title: The Journal of Phytopharmacology - Year 2014, Vol 3, Issue 4
Abstract
The aim of the study was to determine the antibacterial properties of aqueous and methanol extracts of naturally occurring and cultivated Aloe turkanensis. The plant is widely used as a traditional herb by communities in Turkana County, Kenya. However its efficacy has not been established. Aqueous and methanol extract of a naturally occurring whole Aloe turkanensis and cultivated one was obtained. The extracts were tested for in-vitro activity against 4 standard bacterial cultures and a fungal clinical isolate. Benzyl penicillin, Gentamycin and Amphotericin B were used as positive controls. Efficacy data analysis showed that methanol extracts of naturally growing plant inhibited the growth of B. cereus (100 mg/ml), S. aureus (100 mg/ml), and P. aeroginosa (200 mg/ml) with mean diameters of inhibition zones for S. aureus and B. cereus being 18.5±0.7 mm and 16.5±0.7 mm, respectively. Aqueous extract of the plant inhibited the growth of B. cereus and S. aureus at a Minimum Inhibitory Concentration of 200 mg/ml and 50 mg/ml respectively with mean diameter of inhibition zones for S. aureus and B. cereus being 19.75±1.0 mm and 11.5±0.0 mm respectively. Methanol extracts of cultivated A. turkanensis inhibited the growth B. cereus (100 mg/ml), S. aureus (50 mg/ml), E. coli (400 mg/ml) and P. aeroginosa (200 mg/ml) with mean diameters of inhibition zones for S. aureus and B. cereus being 18.5±0.7 mm and 11.5±0.0 mm respectively. There was a significant difference in antibacterial activity between the two plant ecotypes (p<0.05).
Authors and Affiliations
Rukenya Zachary Muthii, Mbaria James Mucunu, Mbaabu Mathiu Peter, Kiama Stephen Gitahi, Okindo Ronald Onzago
Keywords
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