ANTIMICROBIAL ACTIVITY OF NATURAL CHLOROPHYLLIN FROM ENDANGERED MEDICINAL PLANT MIMOSA PUDICA L.
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2016, Vol 8, Issue 4
Abstract
Objective: Chlorophyllin (CHL) belongs to a group of compounds, porphyrins that contain a chelated metal ion in the center of the molecule. The objective of this present study was to extract the Chlorophyllin from Mimosa pudica and to study its antimicrobial activity.Methods: The antimicrobial activity of chlorophyllin from the leaf extract of Mimosa pudica L., was determined in vitro, using well diffusion method against human pathogenic bacteria and fungi, viz., two Gram-negative bacteria: Pseudomonas aeruginosa and Escherichia coli, and two Gram-positive bacteria: Staphylococcus aureus and Klebsiella pneomoniae, and one fungal pathogen, Candida albicans.Results: Chlorophyllin from the leaf extract of Mimosa pudica recorded potential antimicrobial activity against the tested microorganism with the range of 9 mm-18 mm at 25-100 μg ml-1.Conclusion: Natural Chlorophyllin from Mimosa pudica has significant activity against the five pathogenic test microorganisms.Keywords: Medicinal plants, Chlorophyllin, Mimosa pudica, Pathogenic bacteria, Pathogenic fungi
Authors and Affiliations
Rajalakshmi K. , N. Banu
Keywords
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