Antimicrobial resistance pattern of Pseudomonas aeruginosa in a tertiary level hospital in Southern India
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 4
Abstract
Introduction Pseudomonas have now a days become a major cause of nosocomial and community acquired infections They are widely distributed in the hospital environment which makes them difficult to eradicate Paeruginosa has become the leading cause of hospital acquired infection because of its recent trend to gain resistance to most of the drugs used against it causing a multidrug resistance Therefore it is necessary to know the changing pattern so as to achieve a good therapy for pseudomonas infection Therefore this study was conducted to determine the antimicrobial resistance pattern of Paeruginosa with different parameters from the patients attending the tertiary level hospital in Chennai Objective The aim of the study was to enumerate the antimicrobial sensitivity pattern of Pseudomonas infection from various samples in a tertiary care hospital Materials and Methods The study was carried out in Microbiology department of a tertiary care hospital during the period of February 2016 to January 2017 A total of 93 non repetitive clinical isolates of Paeruginosa were collected from different samplesResult In the present study the males 51548 were more affected than females 42452Age distribution showed more to be affected among adults of age 40 and above Amikacin Ciprofloxacin and Gentamicin shows 968 sensitivity Among Cephalosporins highest resistance was observed among 1st generation cefazolin 839 followed by 2nd generation Cefotaxime 172 and Ceftazidime 237 the least was seen among 4th generation Cefepime which showed 65 resistanceAll isolates were sensitive to ImipenemConclusion Restriction of antibiotic usage must be formatted by each institution to combat the emergence of multi drug resistant P aeruginosa Imipenem was the only antipseudomonal drug against which all isolates of P aeruginosa were fully sensitive We recommend a restricted and a more rational use of this drug in this hospital setting Keywords Paeruginosa Antimicrobial resistance Hospital acquired infection
Authors and Affiliations
K. Sharanya, Dinesh Kaliyamoorthi, Chitralekha Saikumar, G. Sridhar, Boopathy Dr
Keywords
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- EP ID EP485890
- DOI 10.18231/2581-4761.2018.0056
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