Antimicrobial Susceptibility Patterns of Uropathogenic Escherichia coli and their Prevalence among Old Age Male and Female People in and around Dhanbad, Jharkhand
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 8
Abstract
Introduction: The susceptibility and vulnerability of UTI is more common in ageing population. E. coli is normally found in human beings as intestinal gut flora. There are so many variant of E. Coli but mainly six groups of E. coli are more hazardous for human population to cause some GIT and urinary tract manifestation. Good evidence and adequate immunity in healthy adults prevents them from poor outcome like kidney failure but in old age as it is its self at a risk factor become more suitable for developing life threating progressive damage of whole urinary track, leads to renal failure that is haemolytic uremic syndrome. The purpose of this study was to evaluate the prevalence and their antibiogram profile of uropathogenic Escherichia coli (UPEC) in old age male and female population around Dhanbad district. Material and methods: A total of 1050 urine samples were collected randomly, for culture and sensitivity tests from the suspected old male and female patients. Their samples were collected in sterile screw capped containers as a mid –stream urine and sent to the Department of microbiology Paliputra medical collage laboratory within one hour of collection. Culture was done by a standard surface streak procedure with MacConkey agar plate. Standard method for urine culture and identification of bacteria for different age group old male and females patients was used. Antibiotic sensitivity tests were done on diagnostic sensitivity plates (DST) by stokes method. Results: Bacterial etiological agent was isolated from 1050 urine samples with highest prevalence of Escherichia coli -45.70 %. The E. coli were highly resistant to Penicillin 43.56%and intermediate level of resistance to Piperacillin/-77%, Levofloxacin and Amikacin followed by Cefotaxime (21.78%). Trimethoprim (11.88%) Sulfamethoxazole (5.94%) respectively.
Authors and Affiliations
Sujeet Kumar Tiwary, S. Sharan, Rajendra Kumar, Krishna Kumari
Keywords
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